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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bcb00d03e649b4354e1079e50ab1f0a9b68fb3a9999e65d07c84cf309afda5a' 
  AND token = 'er6rh0J48BsaEbTJnuuZecsjYtAmKde5T6eilJ9Ky7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}