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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49a68a17860e5aee6b21a7dde5ebff8bcad9767d3b9cc1a2f23f01a0d25269a8' 
  AND token = 'TGGLlQnNoMC2RL70kPDvql05NV7skRU3XPDQagKkGCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}