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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1347a50bec4ad8f806a17a1a594cf52ce596ed393eb1abad4e13298a0723c3ce' 
  AND token = 'EUQlg/v1as4hxfyVQqWsVK7H4O4HMZp/ZPzNTk22l9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}