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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27b7d75b0f3bda79b5a80de89f8ca86701f68f82ac3acf5dca74115908c389ba' 
  AND token = 'ZM0+ESdsLcFkVp+22d4VQuMQYrGqN6Oh3YMqy/1uGzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}