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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a24ee9c23ed1c4a61f60142828c793ea559d1d1d087b0202966a971140158ca9' 
  AND token = 'cH9kz9iL5P6IgeCc5lyMJkCKS6fjbGuWgxOOmQMzgS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}