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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '330876fdbde4832d6b53ec409c28870e56243f3cc926fd6f47e45429a50cee1f' 
  AND token = '+CKpRGAy85uXNLksjKOC6nQfASzkjEO6Xpf6Uki3Ejs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}