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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '125fa8fa8fa0034d1e264c474503db96e806bf0a9ac34e5d32de90520336f610' 
  AND token = 'W2D8DgYUY8sEIWf5ZPFkIX4wpL0b1D2AHYGXQCOk49Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}