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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a8b850e4b410c82bf22938d6f348bc34e3527f9fdec60ac361fbe501e28d234' 
  AND token = 'UyNzcT46hBxvfHAjZJCik4jollsYaCXLlXGEXc8rzPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}