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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f33737838493c821d9fd298c5f375455f0938b757f2149548276fa997e11da18' 
  AND token = 'e9LkpcEi+xPDEg/vzeMCf45DmXSvecbiemdOUiDj3mQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}