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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a82e925895d6673d2a8a31cc443e3319577966b4722bda375241f49b7070d30' 
  AND token = '2slm2PkJUXLPrjYZrFIfdD7/pWwIHWwR1ishpTWO9wI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}