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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb3fc56c186e2270ea08b0e92e63423bb3c3e65b6bcd38146e94cf362e91c25b' 
  AND token = 'E+UJVJI/qUMD0e96ftBB2PczdnBBQZwGiu3NeSb/SU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}