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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c365e1e66ee65684bcd41c4cfa03f0fd65eb92df6693572d5a60e1eb3e6d3eba' 
  AND token = 'eaI6YqVbcZTmV2QhWw1WV4fErGyL/wPNYMCom+Fr8PA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}