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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2744ff2c416004435f967fe22aeb1923fd9741894fc74941b06ffccb440c4e71' 
  AND token = 'zP9HNCWaFVA0bN1IxHEQLpH9cKGmv9lW49gpJ7bS5B0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}