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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39ffec2fa13e648191462f88b8809782bf95ad99b0417c54b7f8bac53a285787' 
  AND token = 'xicTj3jfIJ2u9mJvwZcV3vCpoKVJP5L3wnaiya4Bxpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}