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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27cdbed7eb2e711585c3454f29db5afc77deaa816cb2bb77d5d9a73e3f251d1c' 
  AND token = 'CPsGjwJP2ctljVtfzfb6JAxbuAlRtq/TRtS+LVxkdAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}