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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10dd34d1b9de61056e4a291fab7d5470e172a923e3045eb98a0c0441438e3c83' 
  AND token = 'vVCBdDrcapxzLWQ1kjPmHtOv2TUdB/ZN7HKSJUndrJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}