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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dc9f253c3cf9a9420e538ef7603627ecb429e215aa5265da551d8a10b8cc2d0' 
  AND token = 'u4nZCoRiP46/tyyUloST+xKUwc0PBZ0y87JBd+sXd3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}