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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff87962055a71e193aece4a508020e1a0bef2e51763006670c9e2082ceb221ff' 
  AND token = 'yzAeoCh0Jh1GDnRDYomK6bijOqDMHEwtS/cxVj4M1gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}