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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95d6eef4a503edff5c0c06874aa75b48e9c30d5b678459e7be2733e8c059f870' 
  AND token = 'Yv1itQlGKjHLgSXOyiRDcRZBDePB2SSdh8XT3oppHiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}