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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41ee3c4f3c84f3227b95829e52baeb0799e00a37202ac704944a600d4a04e515' 
  AND token = 'nm7YEBBIY6HjgruQQf9XY+GJct1pDyuHHt6ZVWcv6Rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}