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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44788499fb345eb32de8855781698e3b517d16d4452b0e1aee92ef5ea27a7516' 
  AND token = 'eJ3AH+jtAcRZo9dWFQpWePX3oG4VzkiaX72vuB8i7Ig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}