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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea24b85d6447957b381451bd16b603466c47949a51b16b404385058c74d49e6b' 
  AND token = 'GKfNFnODZhjqwMdYYzHYCqTzKl6gPHEBE4y0E3NWcYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}