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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64074bebbe157f096dc92e7989094e1480809d12e3bacf60de7f5a503b0bd729' 
  AND token = 'XKKoa/3YDEfGSn7BmMvZodvnvI7+t3f4sYH6Fg2IC0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}