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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac12fd40f105598936341ee5375927d421403879d9c6d13c95a6ae4000bf5e76' 
  AND token = '/8/GoU5ksQAlm+B78fj7Ht1yBAvHRGWB21so8GrL4h4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}