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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81509b43fdea6fd991a6ed0893bde3415c1393700f186800c90a82b9eafb81b9' 
  AND token = 'lI9fDMxP84qcOXzI07yjsOkLC2EAgeFAdgDnOyN2tHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}