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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46114091680bf551f20c67900863d816e0b5244611464a707c5222a572f46bad' 
  AND token = 'De03dHsAiEE7mXyVmEXUFjWMTvcp1qQgGzDBTH3Fb/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}