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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eeefa5579c61542f47529e81711a499f4e4a51c8cd26900630bdbfaf9f616c6c' 
  AND token = 'qOn2OmyrlBwbYM+nYSrvS9qJQXJqreP7FbBfzo5H6mQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}