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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ccc64d1ff88623f9a5d6f3143b38a6322db1c287a1843ac28cd330ea56ed8b6' 
  AND token = 'z1xPuSpS+5oqcskEPmwJk+OF9IPgb7GTyN7c64ul9Rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}