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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20dd65260259bc5cfd6f552714cd44cf1980404f37c41f4a2ac192eb21d16688' 
  AND token = 'ILMS4oY2xiGFqb3vDR3Em51INdPTE3l5Tf7ujTnXSdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}