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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '379570f11a0758e98c28e094b86556d54956346ca95ac3342d77636d8b683df7' 
  AND token = 'HedmrYx0mIudisd1az1xNjaK8KG4Zra26pKLBysTzKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}