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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10b9dace748d0ae2c7651b15d5a866fcbe8100cf4a5c4c0e00f62ffdb5cfb5e9' 
  AND token = 'LnsekaF+DkzlSaNI1X0bLA0fUM1qN7zUbZtiRTdSW9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}