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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66f21a70d05ab6e576227d40701ff29f2e97d38f84132f5fdecef2dff410f0d1' 
  AND token = '1Dg7HkEIZnmbU1DZQX/UfupOq/1qbqnUp0E61Zg6iK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}