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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa33302cdef2840f4a9ca21fa2275afdb17623b93f8bd256bee9fc4ae396634d' 
  AND token = '+Lfnsix2YDzwZWwRm9cUD9rfudM7gkEmFJnYc0MfsBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}