SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fd784f2ed50d465c53af847853e24a235b2302ace7924f2c041534e3b0b0ec6' 
  AND token = 'ASRSYb2TiSGamTrEzrF30gWCbSDQ9LR+KWZWv1Y/glg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}