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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '000cb8a72ffb8a5fdef96fd486206a50daf03e6cbdb4188d60034a7389140bfc' 
  AND token = 'LlelrzIiyWIlgFseAosGRDE1KWbZYc72s37O/Xr7eXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}