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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84ad9796e9e30cf10a34d9368751e3e72a8d9a082c50f987475f79c33880b9c8' 
  AND token = 'YiMJ7OttDqy0ge1ZXOGI5+x5xzgjVdyPpjh21TO2/AM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}