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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23d9b933bdd7bf516f4416e6acd44b9d1b35a83844493b8cc2174d6d5216601a' 
  AND token = '1pGk2yd5oPsjiheCCy3H8gwsYT8hXymPNEsGmfzW2nM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}