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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '897e9f5663848951b1f2a378b99a10f34c7e4d180bb1637134df4928e3e2cc1b' 
  AND token = 'mN0fKv0PJnu0o2aMf+cScahfEJQJlJHHXEnNJFYoqaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}