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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b9172cc015360dc3b9163d7f541572d42141932ac90231cd0ba7506504eddde' 
  AND token = 'Ifft08KDNGiPQ1VWvEGMxx68HjeNw75h22xZxYpM68s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}