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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac525c9abd7121a743cf054ecb5044b087778312388de1547dfb190a8edd4f79' 
  AND token = 'EU6FjoZ/z0Z1NIza98igVlJoQGGDTJ+nA+kBLn4Ok0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}