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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '481604f88416f1f3a5e83b85e9105d72416ff390e43edc47e80a1e4bfd0cf56e' 
  AND token = 'ND5/DlgWlXofmSdVDu7+iJEiIAjATMSfpVAOJ211A+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}