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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64274e154fa6ed310ad14191c98d9623921e40eed3327032f0f3cb626e600e0f' 
  AND token = 'GVmFEe0AkFcreM0py58Lf4ItzBWL4KX9rZdXdCrNeRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}