SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2b1061ad91676a3da4949235817996fb8af63997a4741b7d05a788400769742' 
  AND token = 'HBKsr53LFPUl0LNKobAxlPKOsbs21hR9BrFv8+EN/Kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}