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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3320e42aa021e749a5bad506cc411c507acf682c0b9d9959c0c636b68823d157' 
  AND token = 'vWpsIOMqo6wiRgR/tLatn4UfeVN5OksHRUouCiHWpy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}