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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16ef32d1067dea885752d2026a437797a11b772f7f6c4abc2ec830006f488269' 
  AND token = 'VtsYwOVSofU8l67m91TAdNBLMEH+HnYyif8g3v560Gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}