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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db9600da97cb545a729f2847e90183bc5ed9281d1765d4bc4e0819f5a8e6ad3c' 
  AND token = 'M5ptrcfleN/gbd5W2NHGb8/Is7E0Hic7aS8krlTR8Zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}