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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c1db16f5d9f9a812a5e0efe9d63f81b76c4b04d4e891a77f9c9b8199137192' 
  AND token = 'rgrY3mT6cxIh4KdZOJ14h88f0Z8J/W95dLZZ8B6WSCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}