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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad25d15e59f8019854c8522b6c19cd1570b2362556db1a4219f8bd0e67faf21' 
  AND token = 'Tf2rU3iGSlWe/r/mFA0Q/0QsmIKkfqQhO6Ah+XlSsXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}