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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68c1bf4912fe3305922cbb4a3f63b61b58bf9a1d12d6029c305c3c18f8bea0a7' 
  AND token = 'nCKcyLOTMXQnXLLMn28XxgUQFQ7FfASy2uCZbVpnnbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}