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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04c47412169d5451d2e346d3406816a902f428317f2a8452d25a9864a5fb8aa4' 
  AND token = '4mAxV+7RhvUTBmnbj5QQ4Hq7xxyvB7S3WxyTiFAx4bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}